A kallikrein-like enzyme in the aorta of normotensive and hypertensive rats.
نویسندگان
چکیده
منابع مشابه
A kallikrein-like enzyme in blood vessels of one-kidney, one clip hypertensive rats.
Active and inactive kallikrein or a kallikrein-like enzyme are found in the aorta, vena cava, and tail artery and veins of the rat. We studied the concentration of vascular kininogenase in rats with one-kidney, one clip renovascular hypertension and in unilaterally nephrectomized normotensive rats. Six weeks after surgery, active and total vascular kininogenase activity (active plus trypsin-act...
متن کاملAngiotensin converting enzyme variability in hypertensive and normotensive rats.
Recent data have revealed biological and genetic variability in normotensive Wistar-Kyoto rats, which are considered to be the most appropriate control strain for spontaneously hypertensive rats. To investigate the possibility that angiotensin converting enzyme activity could be affected by this variability, we measured plasma and tissue (lung, heart, renal cortex, renal medulla, and adrenal gl...
متن کاملNormotensive and Hypertensive Rats
We evaluated whether vascular kallikrein is altered in rats with genetic or experimental hypertension. Group 1 was infused intraperitoneally with angiotensin II (Ang II) or vehicle for 4 weeks; group 2 was injected subcutaneously with deoxycorticosterone (75 ^unol/kg once a week) or vehicle for 4 weeks; group 3 consisted of uninephrectomized rats on high sodium intake given deoxycorticosterone ...
متن کاملRenal urinary kallikrein in normotensive and hypertensive rats during enhanced excretion of water and electrolytes.
1. Urinary kallikrein excreted by normal rats is significantly increased (P less than 0-001) 2 h after: (a) water loading, (b) water loading plus frusemide, 0-27 mmol (10 mg) per rat, (c) salt loading. In water-loaded rats, 5 i.u. of renin strikingly reduced kallikrein excretion (P less than 0-01) but considerably increased sodium excretion (P less than 0-001). 2. Renal kallikrein, measured by ...
متن کاملMorphology and mechanical properties of the subrenal aorta in normotensive and hypertensive rats.
AIMS This work focuses on the morphological and mechanical changes in the wall of the subrenal aorta in rats suffering from arterial hypertension and chronic renal failure induced by subtotal nephrectomy (NX). METHODS The quantitative structural parameters were assessed using stereological methods. The mechanical properties were determined using uniaxial tensile tests. RESULTS Morphological...
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ژورنال
عنوان ژورنال: Hypertension
سال: 1994
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.23.6.899